We collected information on the movement patterns of wolves (Canis lupus) captured within a 30,000-km² area in the Northwest Territories and western Nunavut. Currently, diamond mining and road construction are occurring in the area used by these migratory wolves for denning. During summers of 1997 and 1998, 23 wolves in 19 different packs were captured and fitted with collar-mounted satellite transmitters. Areas used by these wolves varied seasonally and seemed to correspond to movements of migratory caribou (Rangifer tarandus). Annual home-range sizes (95% minimum convex polygon), averaged 63,058 km² ± 12,836 SE for males and 44,936 ± 7,564 km² for females. Wolves began to restrict movements around a den site on the tundra by late April. They did not depart from their summer ranges until late October, after which they followed caribou to their wintering grounds. Straight-line distances from the most distant location on the winter range to the den site averaged 508 ± 26 km during 1997–1998 and 265 ± 15 km in 1998–1999 (P < 0.01). Home range in summer averaged 2,022 ± 659 km² for males and 1,130 ± 251 km² for females. No difference was detected between sexes or years. All but 2 of 15 wolves returned to <25 km of a previous den, and 2 wolves returned to the same den site. We believe that human activities that disturb or displace denning wolves, or that alter the distribution or timing of caribou movements, will have negative affects on reproductive success of wolves.